Background: Hypertension and malnutrition both became global concern with its increasing prevalence rate worldwide; therefore, blood pressure and nutritional condition now became the most important domains of research in the aspect of public health. This study is also a little effort to contribute in the same domain of public health from the anthropological perspective. Aim: To ascertain the association of Mean Arterial Pressure (MAP) with nutritional status and central obesity of the reference population. Methods: A total of 398 adult Santal individuals (159 males and 239 females), inhabiting mainly in Chotkonda Village and some of its adjacent villages of Debipur under Purba Bardhaman district of West Bengal, India, have been accounted for this cross sectional study. MAP, BMI, MUAC and WHR are the main indicators used in this study to ascertain the individuals’ health status in terms of BP, nutriotional status and central obesity. Results: Study has revealed that an enough percentage of population is suffering from poor health condition in terms of blood pressure, nutritional status and central obesity. There is also found sexual asymmetry only in blood pressure (U= 15796.00**, p= 0.004) and central obesity (U= 9983.00**, p<0.001). Study exhibited weaker positive correlation of MAP with other indicators (rBMI= 0.203, P<0.01; rMUAC= 0.145, P<0.01; rWHR= 0.172, P<0.01). Similarly, a weaker to no association has been found between MAP and other indicators. Conclusion: It has concluded that the nutritional status and central obesity have minimum to no control over determining the blood pressure of the individuals of this particular population. Anthropological significance: It fulfills one of the responsibilities of Anthropological science over an indigenous population by providing the true scenario of their nutritional background as well as blood pressure their control over each other.