Accepted Panels

For a positive Birth outcome, influence of bio genetic factors is very crucial. Emotional stress in a pregnant woman operationally defined by the factor like unwanted pregnancy might interfere with fetal development and result in higher increase of malformations. The interferences may occur directly via psycho endocrinal as autonomous mechanism or indirectly by the way in which a woman might act in a situation of stress, i.e. attempts to provoke abortion, neglect of proper food intake, excessive smoking or abuse of alcohol and drugs. Experiencing one stressful event like job loss, separation, divorce or loss of any one close to them during periconceptional period was associated with varied adverse reproductive outcomes even to women who were not obese and women with less than equal to high school education. Women who experienced stressful life events around the time of conception or early gestation might be at increased risk of delivering infants with certain congenital anomalies.Malformations recognised at birth are predominantly of types which are suspected to have complex genotype as well with environmental contributions to their etiology, and the nature neither of the environmental nor of the genotypic contributions to their etiology is well understood. There is ample evidence all over the world that over all frequency of malformations present at birth would be increased by about 50% if proper documentation can be done. Epidemiologic studies have thrown light on associations between maternal exposure to air pollution in the form of pre term births, pregnancy complications like preeclampsia and gestational diabetes. Different observational studies have been carried out which has stressed on the importance of bio-genetic and socioeconomic factors influencing reproductive outcome and ultimately having impact on public health of the future global citizens. Public health policies must stress on proper documentation of reproductive outcomes to address the issues.