Accepted Panels

Despite modern proceed in treatment and prognosis of breast cancer, a vast difference in incidence and death rates persist across geographic regions. This may be attributed to the differences in trends of the disease by ethnic groups. Although other driving factors may also influence the variation such as differences in transitioned versus transitioning countries, access to screening and cancer care standard, as well as disparity in the risk factors and comorbidity burden, transpiring chiefly as a result of socioeconomic inequalities. The heterogeneity of breast cancer at the molecular level is etiologically and clinically consequential, as it depicts distinct risk factors as well as differences in treatment effectiveness and prognosis. Since breast cancer is a heterogenous disease, the expression of IHC markers manifest utmost implications in management at clinical settings and prognostic factor. Thus, the work attempt to explore trends in breast cancer molecular subtype and presenting profile in the studied population. Examination on the obtained information, revealed Luminal breast carcinoma as a preponderant subtype. The survival rate differs in high income countries and low-middle income countries, attributing to lack of awareness, inequitable access to affordable benefits, though it is favoured with better prognosis if detected early. From the study, majority were reported to have diagnosed at advanced stage, which may attribute to insufficient awareness about the disease or financial constraint or associated social stigma as India is a country where breast cancer topic is not freely discussed. Being the most frequently occurring life-threatening malignancy, its upsurge calls for concern and awareness in various ethnic groups.